BackgroundMalignant melanoma is an extremely aggressive and metastatic cancer. and highly resistant to conventional therapies. Signal transducer and activator of transcription 3 (STAT3) signaling promotes melanoma development and progression. which has been validated as an effective target in melanoma treatment. https://www.roneverhart.com/Mike-and-Ike-Italian-Ice-Candy-5-Ounce-Packs-12-Piece-Box/