Background. Neurofibromatosis type 1 is a genetic disorder caused by loss-of-function mutations in a tumor suppressor gene (NF1) which codifies the protein neurofibromin. The frequent genetic alterations that modify neurofibromin function are deletions and insertions. https://www.roneverhart.com/Black-flower-Reversable-Tote-Bag-E05728-FRS-RB0/