During The absence of this enzyme, as in Crigler-Najjar syndrome variety I, the levels of unconjugated bilirubin will rise, leading to jaundice. Unconjugated bilirubin is h2o-insoluble, and large stages can deposit from the brain leading to a condition called kernicterus. Serious hyperbilirubinemia generally develops in the very first couple of https://www.youtube.com/shorts/IuPMi7CvqAo